Human placental lactogen, estriol patern and the fetal growth

This study was done on 15 idiopathic intrauterine growth retardation [IUGR], 15 [IUGR] associated with hypertensive pregnancy. Determination of serum human placental lactogen [HPL] and estriol [E[3]] were performed serially in the third trimester. Serum levels of HPL [E[3]] were decreased in all [IUGR] pregnacies but more significant in [IUGR] with hypertensive pregnancy and also fetal and placental outcome in this cases showed significant decrease P < 0.02. In conclusion serial determination of serum E[3] and HPL in cases of IUGR and IUGR with hypertension was very important for early evaluation of this high risk groups, so proper therapy can be established